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Clinical
Signs of Canine Hypothyroidism
AKC
Gazette - July 2003 pp 48-51 Coping With Thyroid Disease

Behavioral
Problems
aggression / fearful / shyness / hyperactivity / lack of consentration / fly
catching (biting at imaginary flies) / star gazing (staring in space) /
inappropriate elimination (urine, feces)
Neuromuscular
Problems
seizures / mental dullness / exercise intolerance / neurologic signs
polyneuropathy / lethargy / weight gain / cold intolerance / mood swings
hyperexcitability / stunted growth / chronic infections
Dermatologic
Diseases
dry, scaly skin and dandruff / coarse, dull coat / bilateral symmetrical hair
loss / rat tail, puppy coat / hyperpigmentation / seborrhea or greasy skin
pyoderma or skin infections / myxedema / chronic offensive skin odor
Alterations in
Cellular Metabolism
weakness / stiffness / laryngeal paralysis / facial paralysis / tragic
expression / knuckling or dragging feet / muscle wasting / megaesophagus / head
tilt / drooping eyelids
Reproductive
Disorders
infertility of either sex / lack of libido / testicular atrophy / hypospermia
aspermia / prolonged interestrus interval / absence of heat cycles / silent
heats / pseudopregnancy / weak, dying or stillborn pups
Cardiac
Abnormalities
slow heart rate (bradycardia) / cardiac arrhythmias / cardiomyopathys
Gastrointestinal
Disorders
constipation /
diarrhea / vomiting
Hematological
Disorders
bleeding / bone marrow failure / low red blood cells / low white blood cells /
low platelets
Ocular Diseases
corneal lipid deposits / corneal ulceration / uveitis Keratococonjunctivitis /
sicca or dry eye / infections of eyelid glands (Meibomian gland)
Other
Associated Disorders
lgA deficiency / loss of smell (dysosmia) / loss of taste / glycosuria / chronic
active hepatitis / other endocrinopathies adrenal, pancreatic, parathyroid
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